The University of Nebraska Medical Center receives a national $4.4-million study to see if an over-the-counter medication can reverse the damage from emphysema. Dr. Stephen Rennard with the Department of Internal Medicine says 140 patients with emphysema will participate in this phase of the study.
Dr. Rennard says participants will take either ibuprofen or a placebo daily. Researchers will then measure inflammation to determine the extent of lung repair. He says, “Recent studies support the concept that the ability of the lung to repair damage is suppressed. If you can remove the suppression, then maybe lungs can be repaired. This would be important and entirely new.” He says they already know that ibuprofen blocks the production of prostaglandins and this study hopefully will show the medication blocks that production in the lung.
Four other medical centers in Denver, Boston, Philadelphia and Los Angeles are taking part.