Aspirin therapy for heart attack and stroke prevention may not be a one size fits all issue. A recent British medical Journal “The Lancet” released a study that shows aspirin therapy to address heart disease differs on the size of the individual. The study shows that the common 75 to 100 milligram dose is only effective for those weighing less than 154 pounds and larger, heavier people need a bigger dose. ‘
Dr. Dan Anderson is the Acting Chief of Cardiovascular Medicine at the University of Nebraska Medical Center and says they have often talked about the differences in doses of aspirin depending on the illness. He says. “We’ve often talked about the 81 milligram baby aspirin versus the 325 baby aspirin. We know that 81 is good for strokes, historically we’ve studied 325 and even more for heart attacks and cardiovascular disease, so finding out there may be a not one-size-fits-all is an important finding.” He says a larger male may take a little more medicine to have the effect that we want to prevent the progression or severity of a disease event.
Dr. Anderson says physicians always worry about a bleeding event in the case of stroke. He says at his practice he talks to patients about the risk of 81 milligrams or 325 milligrams. He says when someone has a severe cardiovascular disease they are most often put on the 325 dose. For preventative, the 81 milligram dose is adequate but Dr. Anderson says this study now has him thinking twice whether to up that amount.
Dr. Anderson says there will likely be more studies on the issue in the near future.